General name: florfenicol soluble powder

English Name: florfenicol soluble powder

Hanyu Pinyin: fubennikao kerongxing Fen

Florfenicol

本品为白色或类白色粉末。

Pharmacodynamics: florfenicol belongs to amide alcohol broad-spectrum antibiotics and bacteriostatic agents. It plays a role by inhibiting the synthesis of bacterial proteins by binding with ribosomal 50S subunit. It has strong antibacterial activity against a variety of gram-positive and Gram-negative bacteria. Pasteurella haemolyticus, Pasteurella multocida and Actinobacillus pleuropneumoniae were highly sensitive to florfenicol. The antibacterial activity of florfenicol against many microorganisms in vitro is similar to or stronger than that of thiamphenicol. Some bacteria resistant to amidol due to acetylation, such as Escherichia coli and Klebsiella pneumoniae, may still be sensitive to florfenicol. It is mainly used for bacterial diseases of pigs, chickens and fish caused by sensitive bacteria, such as respiratory diseases of cattle and pigs caused by Pasteurella haemolyticus, Pasteurella multocida and Actinobacillus pleuropneumoniae. Typhoid and paratyphoid fever caused by Salmonella, chicken cholera, chicken dysentery, colibacillosis, etc; Bacterial septicemia, enteritis and erythroderma of fish caused by Pasteurella, Vibrio, Staphylococcus aureus, Aeromonas hydrophila and enteritis bacteria.

Pharmacokinetics: florfenicol is absorbed rapidly after oral administration. The therapeutic concentration can be reached in the blood after about 1 hour, and the peak blood concentration can be reached in 1 ~ 3 hours. The bioavailability is more than 80%. Florfenicol is widely distributed in animals and can penetrate the blood-brain barrier. It is mainly discharged from urine in its original form, and a small amount is discharged with feces.

(1) Macrolides and lincolamines have the same action target as this product. They both bind to the 50S subunit of bacterial ribosome, and can produce mutual antagonism when combined.

(2) It may antagonize the bactericidal activity of penicillins or aminoglycosides, but it has not been proved in animals.

Amide alcohol antibiotics. It is used to treat bacterial infection caused by chicken sensitive bacteria.

Based on this product. Mixed drink: 0.33g ~ 0.66g chicken per 1L of water for 3 ~ 5 days.

This product has strong immunosuppressive effect when it is higher than the recommended dose

(1) The laying period of laying hens is prohibited.

(2) Animals with severe immune deficiency during vaccination or immune function are prohibited.

Chicken 5 days.

30%

Sealed and stored in a dry place.