Ciprofloxacin hydrochloride berberine hydrochloride premix_Zhejiang Kangmu Pharmaceutical Co., Ltd

【Veterinary drug name】:

Generic name: Ciprofloxacin Hydrochloride berberine hydrochloride premix

Trade name: binghuangdi

English Name: CI profloxacin hydrochloride and berberine hydrochloride premix

Hanyu Pinyin: yansuan huanbingshax ing

【Main components】:

Ciprofloxacin hydrochloride, berberine hydrochloride

【Character】:

This product is light yellow powder.

【Pharmacological action】:

Pharmacodynamics: ciprofloxacin is the second generation of fluoroquinolones and a broad-spectrum bactericide. Its bactericidal effect depends on the drug concentration, and the sensitive strain can be killed 20 ~ 30 minutes after treatment. It has an effect on the replication of bacteria in quiescent and growing stages. It is generally believed that it interferes with DNA supercoiling and DNA synthesis by inhibiting bacterial DNA gyrase (type II topoisomerase). Ciprofloxacin is effective against a variety of gram-negative bacilli and cocci Including Pseudomonas aeruginosa, Klebsiella, Escherichia coli, enterobacter, Campylobacter, Shigella, Salmonella, Aeromonas, Haemophilus, proteus, Yersinia, Serratia and Vibrio. Other sensitive bacteria include chlamydia, mycoplasma and Mycobacterium. Not recommended for streptococcal infections. Berberine hydrochloride has broad-spectrum antibacterial effect. It has antibacterial effect on a variety of gram-positive and Gram-negative bacteria in vitro, including hemolytic streptococcus, Staphylococcus aureus, Vibrio cholerae and meningococcus. The two drugs often have synergistic effects. Pharmacokinetics: the elimination half-life of eel after oral irrigation is 51.9 hours, the peak time is 0.9 hours, and the maximum peak concentration is 0.46 μ G / ml (single dose is 10.0mg/kg); With 10 μ G / ml for 48 hours, and the maximum peak concentration is 0.12 μ G / ml, the peak time is 0 2 hours with a half-life of 15.5 hours.

【Function and use】:

Antibiotics. It is used to treat stubborn bacterial diseases of eel.

【Usage and dosage】:

Based on this product. Mixed feeding: Eel 15kg per 1000 kg feed. Feeding for 3-4 days.

【Adverse reaction】:

According to the prescribed usage and dosage, no adverse reactions have been found.

【Withdrawal period】:

500 degrees a day.

【Storage】:

Keep it in a cool and dry place.